A bacterial cell has multiple protein assemblies, which form higher order cellular structures and play important roles during cellular division [ 1].
However, this would require multiple de novo assemblies, which for the short read data generated in this study is likely to be highly fragmented and thus of limited utility.
On paper, the savings in drilling more than offsets the extra cost of multiple pipe assembly, which ultimately means that plastic is less expensive than the lifecycle operation of the drill rig.
In general, for genomes with multiple assembly updates, such as human and mouse, we observe fewer probes mapping to improved assemblies, which may indicate that correcting assembly errors enhances probe mapping by removing probes designed against lower quality regions of the assembly.
The assemblies generated with k-mer lengths of 23, 25, 27, and 29 base pairs were combined through meta-assembly which extends contigs found in multiple assemblies and retains contigs found in only one.
It can also significantly reduce the amount of time required for assembly, which is an important consideration when generating multiple assemblies [ 39].
The initial assembly of pooled 454 BAC sequences showed 40% inflation compared with estimated insert sizes, which likely was caused by multiple assemblies of repetitive sequences.
Finally, the ' cluster' access point allows those clusters which have been split into multiple assemblies to be browsed.
Multiple assemblies were generated with varying parameters to account for potential gene collapse or artificial duplication/expansion, which is a significant problem for regions with shared sequence or many repeats.
Multiple assemblies were conducted to calibrate the optimum kmers parameters.
