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In any case, it is more likely that multiple antigenic challenges combined with maturing lymphocytes with a genetic lesion, for example, an intrauterine translocation, were involved in the genesis of ALL.
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The possibility of multiple antigenic conformations or intermolecular epitopes cannot be ruled out when considering surface antigen structure.
multiple antigenic peptide.
Tam developed the multiple antigenic peptide (MAP) system to improve the poor immunogenicity of subunit peptide vaccines [23].
These were synthesized in combination as three multiple antigenic peptides (MAPs).
αβ T-cell receptors (TCRs) recognize multiple antigenic peptides bound and presented by major histocompatibility complex molecules.
Tam developed the multiple antigenic peptide (MAP) system using a non-immunogenic lysine-based dendritic scaffold to improve the immunogenicity of subunit peptide vaccines (Tam, 1988).
Spleen cells from calpain multiple antigenic peptide (MAP -immunized BALB/c MAP -immunizedIFNγ upon stimulation with MAP or soluBALB/crmicetigen producedIFNγ(SWAP).
Therefore, the dendritic tandem multiple antigenic hTERT epitope peptides combined with MDCs may represent a powerful, broad-spectrum anti-tumor vaccine.
This study demonstrated, for the first time, an innovative strategy of inserting multiple antigenic modules, up to 45 modulesules, in a single capsomere.
To the best of our knowledge this is the first study describing the use of synthetic multiple antigenic peptides for the diagnosis of dengue infection.
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