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Ye, X. et al. An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies.
The chitosan-based film, which can be made into any size and shape, is capable of delivering multiple anticancer agents to a tumor site as it dissolves over several weeks.
After being tethered to the platinum(IV) complexes, the wogonin derivative provided multiple anticancer effects, especially in compound 10, a fusion containing wogonin and cisplatin units.
The natural cyclopeptide FR235222 is a potent HDAC inhibitor displaying relevant multiple anticancer effects and is considered an attractive lead compound for the generation of new and more effective antitumor therapeutics.
This nanosystem was developed for targeted co-delivery of multiple anticancer drugs to p32-overexpressing tumor cells and peritumoral lymphatic vessels, using LyP-1 peptide as active targeting ligand, with the aim to achieve a targeted combinatorial chemo/angiostatic therapy and MDR reversal.
In agreement to our computational prediction, niclosamide has been recently shown multiple anticancer effects in tumors of the ovary and colon, and also in leukemia and myeloma [19 24].
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MgHECSPz was designed to improve the potentiality in multiple approach anticancer therapy.
Multiple traditional anticancer agents, including anthracyclines and alkylating agents, are found to stimulate massive ROS generation in cancer cells [39].
The first aim of this study was to evaluate the efficacy of combination antiemetic therapy with a 5-HT3RA plus NK-1RA and Dex in patients receiving chemotherapy for high-grade bone and soft tissue sarcoma using multiple HER anticancer agents.
Eligible patients were 15 years of age or older, had confirmed high-grade malignant bone and soft tissue tumors, and were scheduled to receive chemotherapy with multiple emetogenic anticancer drugs.
In this review article, the major focus has been paid to the applications of isoxazole compounds in treating multiple diseases, including anticancer, antimicrobial, anti-inflammatory, etc. Strategies for compounds design for preclinical, clinical, and FDA approved drugs were discussed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com