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These sequences were analyzed through multiple annotation modules, including repetitive sequence annotation, gene prediction, protein function and domain structure annotation.
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Validation of the extracted modules by multiple annotation allows for the assessment of confidence measures assigned to the modules in a protein pathway context.
Annotation of the rhesus GeneChip® is under continuous revision with large percentages of probesets under multiple annotation systems having undergone multiple reassignments between March 2007 and November 2008.
The annotation module provides a user-friendly interface to annotate variants input by the users.
The feature extraction and annotation module then maps TARs to existing genome annotation.
G-Portal further incorporates both a query module and an annotation module for users to search metadata and to create additional knowledge for sharing respectively.
The functional annotation module, AutoAnnotate, automatically assigns preliminary functional annotations to predicted proteins using precedence-based rules that favor highly trusted annotation sources.
They include pre-processing (Module 1), annotation (Modules 2 6), quantitative analysis (Modules 7 8) and database querying (Module 9) (Fig. 1).
Finally, by using Bowtie to map sRNAs against user-supplied sequence files and directly transferring the resulting annotations to the MySQL database, we provide a simple way of adding multiple sets of similarity-based annotations (Module 6).
ORFs that include GH10 or GH11 xylanase modules commonly showed multiple catalytic modules.
Multiple methylation modules exhibit significant enrichment.
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