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ET-1 has been targeted in the experimental treatment of portal hypertension in multiple animal trials.
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Multiple pre-clinical animal trials have been conducted, but with conflicting outcomes.
During the past few years, the best-characterized apoptosis marker, annexin V, a calcium-dependent phospholipid binding protein [ 40, 41], has been extensively investigated in multiple animal models as well as in clinical trials [ 42].
Improved therapeutic efficacy of targeted nanocarriers has been established in multiple animal models of cancer, and currently more than 120 clinical trials are underway with various antibody-containing nanocarrier formulations [ 2].
Several variants of this chimeric transcription factor potently induced angiogenesis in multiple animal models and one variant was later used in gene therapy clinical trials to treat ischemia.
The three candidates had shown good results in animal trials.
A former vegetarian, he finds animal trials distressing.
Animal trials are ready to commence on this surgical workstation.
Inclusion criteria consisted of controlled animal trials.
Three animal trials were conducted to further validate the assay.
Other exclusion criteria were: case reports, articles written in other languages, animal trials, and reviews.
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