Toward a definition of a valid animal model of alcoholism: multiple animal models for multiple diseases.
The effectiveness of this device has been tested in multiple animal models, from rats to non-human primates.
H3 antagonists have been shown to enhance attention and cognition in multiple animal models.
The ability of juvenile animals to regenerate calvarial defects has been investigated in multiple animal models, including mice.
An antibody-modified nanoparticle encapsulating a pH-sensitive taxane prodrug, and targeting an overexpressed receptor in tumours, improves the tolerability and anticancer efficacy of the active drug in multiple animal models.
Immune responses following gene transfer of coagulation factor IX (FIX) for the treatment of the bleeding disorder hemophilia B has been extensively investigated in multiple animal models.
N,N′-disubstituted urea-based soluble epoxide hydrolase (sEH) inhibitors are promising therapeutics for hypertension, inflammation, and pain in multiple animal models.
Atrial natriuretic peptide (ANP), an endogenous hormone synthesized by the cardiac atria, has been shown to improve renal function in multiple animal models of acute renal failure.
The efficacy of DCA treatment has also been demonstrated in functional recovery during reperfusion in multiple animal models [50 53].
Using these precisely controlled APRV settings, a number of studies have shown that P-APRV recruits and stabilizes the alveoli and alveolar ducts [54 56] and reduces the incidence of ARDS in multiple animal models [5, 57, 62].
First, these BLA neurons were activated in multiple animal models of anxiety (e.g., open field test, elevated plus maze test).
