Sentence examples for multiple angiogenic mediators from inspiring English sources

HIF-1 promotes vascularization by inducing the expression of multiple angiogenic mediators such as VEGF, placental growth factor, angiopoietin 1 and 2, and PDGF-BB [ 60].

The efficacy of TF/VIIa/PAR-2-mediated activation of angiogenic mediators is greater than that induced by PAR-1 signaling [ 38].

Although EGF has been demonstrated to induce expression of angiogenic mediators, potential interactions in CRC between EGF-mediated signalling and the hypoxia/HIF pathway remain uncharacterised.

The angiogenic mediators in maternal circulation are predominantly of placental origin.

Kidneys, liver, spleen, and heart were excised to quantify the expression of angiogenic mediators and markers of progenitor cells.

The authors have demonstrated that by altering the balance between angiostatic and angiogenic mediators, IFNγ disrupts the granuloma vascularization and leads to a hypoxic central core.

This result indicates that fullerene-containing materials serve as a potent antiangiogenesis inhibitor that can simultaneously target multiple angiogenic factors.

The angiogenesis is a co-ordinated process that requires the participation of multiple angiogenic factors.

At later stages, a general decrease in gene expression occurs, including genes encoding mitotic factors or angiogenic mediators such as CYR61, EPAS1, MDK and MYC.

Activated inflammatory cells promote angiogenesis, tumor cell proliferation and metastasis through the production of angiogenic mediators, growth factors, chemokines and proteases [2], [24] [26].

However, the benefits of anti-angiogenic therapy can be limited by redundant mechanisms of angiogenesis control, a problem that may potentially be overcome by targeting multiple angiogenic pathways or the use of broad spectrum angiogenic inhibitors [6].