Sentence examples for multiple angiogenic genes from inspiring English sources

HIF-1α has been shown to be required for the expression of multiple angiogenic genes, including VEGF, PDGF, and TGFα [ 3].

Abnormal activation of FoxM1 leads to overexpression of multiple angiogenic genes, such as MMP-2, Cav-1, ZEB1 and ZEB2, which result in overexpression of multiple pro-invasion and -metastasis molecules [ 28, 33– 33].

In vitro data suggests that thalidomide has anti- angiogenic activity, blocking the expression of multiple angiogenic agents (D'Amato et al, 1994).

Our custom-made real-time PCR based array of 72 genes revealed multiple angiogenic growth factors showing more than 2-fold increase as compared to EmpMSCs (Table S3).

MiRNAs with multiple targets are able to serve the purpose of co-regulating a group of functionally related genes, such as multiple angiogenic factors under strict spacio-temporal conditions.

Hypoxia-inducible factor (HIF-1) is the key transcription regulator for multiple angiogenic factors and is an appealing target.

However, other downregulated genes belonged to cellular invasion, anti-apoptosis, proliferation, and angiogenic genes.

In addition, primary myoblasts can carry exogenous angiogenic genes that encode angiogenic factors to promote therapeutic angiogenesis.

This result indicates that fullerene-containing materials serve as a potent antiangiogenesis inhibitor that can simultaneously target multiple angiogenic factors.

The angiogenesis is a co-ordinated process that requires the participation of multiple angiogenic factors.

This stabilises hypoxia inducible factor-1α and therefore de-repress the transcription of various angiogenic genes.