Sentence examples for multiple alterations of from inspiring English sources

Cerebral angiography can show multiple alterations of the cerebral blood vessel caliber.

Multiple alterations of the Nrf2 pathways have been associated with the development and progression of chronic disorders.

Our studies also took into account the multiple alterations of membrane components in hem1Δ deletion strains which additionally affect membrane properties.

Our data show that deletion of Cx43 in SCs leads to multiple alterations of gene expression in prepubertal mice and primarily affects GCs.

In addition, human HNSCC often display multiple alterations of the PI3K pathway, including increased PIK3CA expression, PIK3CA mutations, Akt amplification and mTOR activation (Pedrero et al, 2005; Herzog et al, 2013).

Data from literature suggest that a more robust activity of novel dual PI3K/mTOR inhibitors, compared with either PI3K or mTOR inhibitors, is required for efficient suppression of tumour growth when multiple alterations of the PI3K pathway exist (Sabbah et al, 2011).

Colorectal cancer (CRC) results from the accumulation of multiple alterations in the (epi) genome of the epithelial cells that line the large intestine.

These results suggest multiple alterations in metabolism of lipids and specific fatty acids in cancer patients.

Malignant progression involves an accumulation of multiple alterations in cellular growth control over an extended period of time.

The inefficiency of metastasis is explained in this model by the low probability that any given cell within the primary tumor will acquire all of the multiple alterations required for the successful implementation of the metastatic cascade.

Thus, exposure of female mice to cocaine during pregnancy resulted in multiple alterations in the methylation states of offspring DNA, and some of these cocaine-related effects could persist through at least the prepubertal period of 30 days postnatum.