Sentence examples for multiple alterations are from inspiring English sources

Multiple alterations are known to occur in the FGF axis in prostate cancer.

The multiple genetic alterations are caused by multiple environmental carcinogenic substances or factors, each of which usually exists only at minute concentrations and does not exert any major impact alone except under particular occupational, iatrogenic, and locally geographic conditions.

These multiple genetic alterations are considered to be a direct reflection of the multiple steps involved in carcinogenesis.

Multiple genetic alterations are required for cancer development, and understanding the mechanisms that promote and enhance DNA damage is important.

Multiple genetic alterations are generally found in solid tumours and an increasing complexity of chromosomal aberrations is typically associated with tumour progression (Albertson et al, 2003).

Multiple genetic alterations are involved in gliomagenesis leading to an aberrant activation of key pathways involved in mitogenic signaling and cell cycle control.

Accumulation of multiple genetic alterations is known to be associated with the development and progression of cancer (Loeb et al, 1991).

At the moment, the stepwise development of cancer with the gradual accumulation of multiple genetic alterations is the most widely accepted model [ 8].

Multiple discrete alterations were observed on chromosome arms frequently implicated in breast cancer, including 1p (four deletions), 8q (eight amplicons) and 17q (seven amplicons and four deletions).

This is not to suggest that molecular events are not important, but morphology, the visual consequence of a chaotic interplay of multiple molecular alterations is readily analysed and interpreted.

Multiple genetic alterations were reported to be more common in younger patients with papillary thyroid cancer [ 19], while younger patients with colorectal cancer showed a high frequency of KRAS mutations [ 20].