Sentence examples for multiple allelic polymorphisms from inspiring English sources

In contrast, in areas of frequent endemic transmission, such as Togo, multiple allelic polymorphisms would be expected (9 ).

Common CNV polymorphisms (i.e. frequency > 1%) often with multiple allelic states defined by variations in copy number and/or genomic structure; and rare CNVs, that typically lead to deletion or duplication of larger genomic segments and exist in fewer allelic states (i.e., hemizygous or trisomic).

Thus, the slow acquisition of immunity to naturally acquired malarial infection is likely to be at least partly due to the existence of polymorphism in the target antigens of protective immunity against the parasites (i.e. multiple allelic forms of an antigen-coding gene) [11].

Expressed MHC loci typically show very high levels of diversity, which correspond to allelic polymorphisms [11].

However, allelic polymorphisms of these genes can only partly explain the variance of the clinical course, because the genetic background of RA involves multiple genes [ 4].

They could be polymorphisms that are maintained in populations by processes similar to those that maintain allelic polymorphisms [ 30].

The data also led to the hypothesis that some gene insertions and deletions might be polymorphisms, similar to allelic polymorphisms.

However, functional relevant allelic polymorphisms of MMP genes, specifically the MMP1 polymorphism, could influence the severity of the disease.

Fifteen loci showed reliable amplification, and allelic polymorphisms could be scored consistently.

A bioinformatic assessment of allelic polymorphisms within and near candidate genes was also performed.

Finally, nine out of 12 loci provided sufficient allelic polymorphisms and robust PCR characteristics (Table 1).