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Promoter activity of the single SNPs or multiple allelic changes corresponding to the genotype patterns (GPs) was tested.
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*Consequences of allelic changes are only indicated for differential SNPs (i.e. alleles showing > 50% allelic frequency difference in any selected strain as compared to the susceptible strain).
Third, ZFNs can be used to induce a wide variety of allelic changes covering small or wide deletions or insertions.
To account for multiple allelic states, indels were analyzed as class explanatory variables in PROC MIXED.
The reasons of this multiple allelic effects are only understood in part.
Furthermore, no differences at the expression level of the protein were found with allelic changes (47).
In contrast, in areas of frequent endemic transmission, such as Togo, multiple allelic polymorphisms would be expected (9 ).
Relationships between singletons with multiple allelic differences are not robust because they can be connected to other nodes equally.
Initially this was carried out using the multiple allelic loci detected by single SSR, RFLP or SNP markers.
An example of this is shown in sample question 4, which addresses the concept of multiple allelic series.
Multiple allelic sequences of each candidate gene were aligned by the CLUSTAL W method (Thompson et al. 1994) using MEGA5.
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