Sentence examples for multiple alignment problem from inspiring English sources

In the post-genomic era,the growing complexity of the multiple alignment problem has lead to the development of novel methods that use a combination of different alignment algorithms [22], [23], [24], [25] or that incorporate biological information other than the sequence itself [26], [27].

Therefore, we examined which is more suitable for the multiple alignment problem.

If the PPI networks were complete and exact, the multiple alignment problem would simply be to find maximally weighted cliques.

The multiple alignment problem is then reduced to to subsequent alignment steps of individual sequences to a growing multiple alignment graph.

We chose to employ the multiple alignment method of [ 25] who applies partial order graphs (POG) to the multiple alignment problem.

Existing RNA-seq analysis pipelines provide heuristics for addressing the multiple alignment problem, however, they do not explicitly consider their genomic causes.

The protein families used as benchmark test sets were selected to provide a variety of different multiple alignment problems (Figure 9).

In this paper, we introduced a new optimization algorithm for the segment-based multiple-alignment problem.

Current RNA-seq analysis pipelines handle the multiple-alignment problem in both the alignment and assembly steps.

The optimization method that we introduced herein is inspired by the so-called progressive approach to multiple alignment introduced in the 1980s for the classical multiple-alignment problem [ 17].

Finally, we did not test any of the numerous pairwise aligners or pairwise synteny mapping methods, as our work focuses on the multiple genome alignment problem.