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From the start, the T-Coffee framework made it possible to turn any pair-wise method into a multiple alignment method, thus opening the way to two major developments undergone by multiple aligners these last years: meta alignment methods and template-based alignments.
brasiliensis AP2-domain proteins of around 60 amino acids were then aligned using MUSCLE software [ 43, 95], which uses a progressive multiple alignment method.
The full AP2-domain sequences derived from Hevea and Arabidopsis AP2-domain proteins of around 60 amino acids were then aligned using MUSCLE software [ 85, 86], which uses a progressive multiple alignment method.
In their article, the authors used the multiple alignment method to reconstruct the evolutionary tree.
Our method takes only 18 seconds to complete the clustering analysis result while it takes more than 19 hours for the multiple alignment method.
It took us 60 minutes 31 seconds to finish the complete alignment for these 21 sequences by using multiple alignment method [14] whereas we just need 6 seconds to get the result.
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Our method is easier and quicker in handling whole or partial genomes than multiple alignment methods.
Whole or partial genomes can be handled more easily and more quickly than using multiple alignment methods.
There is no need to reconstruct the genome space for any subsequent application, whereas in multiple alignment methods, realignment is needed for adding new sequences.
There is no need to reconstruct the genome space for subsequent applications, whereas in multiple alignment methods, realignment is needed to add new sequences.
Multiple alignment methods based on probabilistic consistency have demonstrated great promise in the context of amino-acid alignment [75] and aligning collinear genomic regions [33], and in principle, could be extended to genome alignment with rearrangement.
More suggestions(15)
multiple model method
multiple platform method
multiple inverse method
multiple assignment method
multiple grid method
multiple imputation method
multiple alignment position
multiple access method
multiple alignment tree
multiple scale method
multiple alignment profile
multiple port method
multiple staining method
multiple alignment generation
multiple regression method
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