If blood pressure is refractory to multiple agents, clinicians should consider an evaluation for secondary forms of hypertension.
Architectural Agents considers material and digital buildings as agents that both endure pain and inflict it.
Clinical syndromes are infrequently specific for single pathogens; thus, assays are needed that allow multiple agents to be simultaneously considered.
The most appropriate application of theories and models will be a locally-selected, culturally-relevant, pragmatic combination of strengths from a variety of theories that best consider the multiple agents, external factors, and internal influences.
For example, 100 FDA approved drugs would result in about 5,000 two-drug combinations, and the number increases exponentially if we consider combinations of multiple agents.
Of course, for the majority of bipolar patients on other psychotropic medications other than lithium, weight gain should be considered as due to multiple agents such as antipsychotics, valproate and some antidepressants.
In this context, it is important to consider the combination of multiple agents and/or the use of less selective drugs, in order to inhibit multiple pathways at the same time, or the same pathways at multiple levels [328].
Because additivity or synergy of TDCs with different modes of action has been demonstrated, and background exposure to many TDCs is common, risk assessments should consider simultaneous exposures to multiple agents and account for these interactions.
The combination treatments using chemotherapeutic agents with distinct molecular mechanisms are considered more promising for higher efficacy; however, using multiple agents contributes to added toxicity.
We consider how to combine the preferences of multiple agents despite the presence of incompleteness and incomparability in their preference relations over possible candidates.
