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The different surgical procedures can address multiple affected joints on the same hand and generally have good results, but there can be complications from surgery, such as nerve or artery injury [ 9, 10].
Multiple concurrent injections would eliminate the 30-day wait between single treatments and allow for rapid and effective treatment of patients with multiple affected joints, a significant advantage for both patient and physician.
A third option is that as waiting lists decrease, patients with multiple affected joints in the same hand or bilateral contractures can receive more than one procedure in a single calendar year.
The ability to give multiple injections, without the need to wait 30 days between treatments, would allow for a more rapid and effective treatment of multiple affected joints in a fashion similar to the surgical paradigm, and constitute a significant advantage for both patient and physician.
However, it should be noted that the site-specific results should be interpreted cautiously; the number of variables complicates the model and its interpretation, and the presence of multiple affected joints in a proportion of patients is also likely a confounding factor.
Similar(53)
This open-label pilot study was designed to examine the safety, efficacy, and multiple-dose pharmacokinetics of injecting two cords (affected joints) with multiple doses of CCH concurrently into the same hand in subjects with DC and multiple contractures.
Question nodes are of several types: yes/no; yes/no/uncertain; single selection multiple choice question; multiple choice questions; graphic representations of anatomy, e.g. to select affected joints in a patient with joint pain; and user entries, which can be entry of free text or entry from pull down menus.
Surgical correction of affected joints is often used to correct multiple contractures on the same hand during the same procedure.
The development of degenerative changes adversely affects the normal morphology of the affected joints.
Because levels of serum biochemical markers for arthritis depend on the circulating concentrations of molecules derived from the affected joints, the marker level is expected to be higher in patients with multiple joint involvement than in patients with a specific joint site.
Rheumatoid arthritis (RA) is an autoimmune disease affecting about 1% of the world population and characterized by chronic inflammation of multiple joints, proliferation of the synovial cells, and destruction of the cartilage and bone of the affected joints.
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