Systemic Rbpj deletion in mice results in embryonic lethality prior to 10.5 days of gestation due to the accumulation of multiple abnormalities, such as growth retardation, defective somitogenesis, and abnormal placental development.
"Multiple abnormalities" were cited, but no clear explanation for the death.
Multiple abnormalities occur in polyostotic fibrous dysplasia, in which affected bone is replaced by fibrous connective-tissue matrix.
A remarkable feature of malformations in vertebrates including man is the association of multiple abnormalities in complex syndromes.
The Fanconi syndrome is a group of diseases in which there are multiple abnormalities in renal-tubular function.
Multiple abnormalities may be associated with MRKH syndrome, and it appears to overlap other syndromes.
Lck-GM-CSF transgenic mice displayed a dramatic phenotype, characterized by splenomegaly, lymphadenopathy, thymic atrophy, and multiple abnormalities in blood cell populations.
In this paper, robust outlier statistics are investigated, focussed mainly on a high level estimation of the "masking effect" of inclusive outliers, not only for determining the presence or absence of novelty-something that is of fundamental interest but also to examine the normal condition set under the suspicion that it may already include multiple abnormalities.
Specifically, the report says the EPA's Midwest branch knew in June 2015 that Flint hadn't treated its water correctly and that "residents had reported multiple abnormalities in the water, and test results from some homes showed lead levels above the federal action level".
Examination of unf knockdown MBs through early pupal development revealed multiple abnormalities.
In contrast, retinal microvessels of sEng-expressing mice were characterized by multiple abnormalities, particularly in the superficial vascular plexus.
