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These processes are prone to multiple aberrations in cancers with varying outcomes.
Cells with more than four of the same type of aberration were scored as multiple aberrations.
Our study demonstrates that most of our excellent responders had multiple aberrations.
A computational method designed to identify driver mutations within protein kinase datasets successfully identified multiple aberrations in the FGF/FGFR machinery [ 4].
In patient #2, who also achieved a durable PR (14 months) on anastrozole and everolimus, multiple aberrations were seen as well.
Our data show, for the first time, that in acute pancreatitis complicated by vital organ dysfunction multiple aberrations occur in lymphocyte signaling profiles.
Similar(44)
We can deduce how individual tumors evolved from common ancestor cells by comparing the aberration patterns of multiple genetic aberrations.
If there were multiple genomic aberrations, the lineage of multiple tumors could be deduced from the patterns of the aberrations.
However, the first method requires well-separated atomic columns and the second can have difficulty measuring multiple simultaneous aberrations.
Large-scale genomic studies have identified multiple somatic aberrations in breast cancer, including copy number alterations and point mutations.
Multiple chromosomal aberrations were identified, some of them located in regions with known tumor suppressor genes and oncogenes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com