Sentence examples for multiple Notch ligands from inspiring English sources

Multiple Notch ligands are expressed within the developing mammalian CP [13], with no known requirement for Notch signaling yet described.

Multiple Notch receptors and ligands are expressed in the epidermis and hair follicles during embryonic development and the adult stage.

The complexity of the Notch system in vertebrates is illustrated by the existence of multiple Notch receptors and ligands, each having a distinct expression profile.

In this study, we demonstrated that mouse osteoclast precursors expressed multiple Notch receptors and ligands during osteoclastogenesis, but Notch2/Dll1 axis enhanced and Notch1/Jagged1 axis suppressed osteoclastogenesis selectively.

Similarly, another study reported higher expression level of multiple Notch receptors and ligands in IDC compared with normal breast tissues [ 13].

For example, tumor necrosis factor-α converting enzyme (TACE/ADAM17) is essential for the phorbol ester stimulated shedding of the ectodomains of various membrane-anchored proteins [10], and Kuzbanian/ADAM10 is involved in the ectodomain shedding of multiple substrates, including ephrin, Notch ligands, and cadherins [11] [15].

A distinguishing feature of both proteins is their ability to interact with TGFβ family growth factors, Notch and Notch ligands, and multiple elastic fiber proteins.

Protein jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling.

Protein jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling, which influences neuronal function and development [20].

The receptors are activated via interactions with Notch ligands, which are also type-I transmembrane proteins with multiple EGF-like repeats in their extracellular domain (D'Souza et al, 2008).

The many facets of Notch ligands.