Sentence examples for multinational randomized trial from inspiring English sources
The approval was based on phase III multinational, randomized trial METRIC [ 56, 57].
In brief, it was a multinational randomized trial with a 2 × 2 factorial design that tested two pairs of interventions.
This manuscript constitutes, to our knowledge, the first multi-centre, multinational, randomized trial evaluating the potential efficacy of oral nutritional supplementation on wound healing in diabetes.
The Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen Detected Diabetes in Primary Care (ADDITION) study is a multinational randomized trial involving 3,057 screen-detected type 2 diabetic patients that compares the effectiveness of an intensified multifactoral treatment with usual care on 5-year cardiovascular morbidity and mortality rates in a primary care setting (10).
Recently published results of a multinational, randomized trial on the thrombin receptor antagonist vorapaxar in acute coronary syndromes showed no significant reduction of death from cardiovascular causes, myocardial infarction, or stroke if vorapaxar was added to standard therapy, but the risk of major bleeding, including ICH, was significantly increased [ 19].
62 This study compared health-related quality of life over 12 months in patients taking insulin lispro with those taking human regular insulin, in the setting of an open-label multinational randomized trial involving 468 patients with type 1 diabetes mellitus and 474 with type 2 diabetes mellitus.
Future large, multinational, randomized trials are required to confirm our results.
Development of clinical trial networks for rare diseases can facilitate the conduct of multicenter and even multinational randomized trials.
Following a multinational randomized controlled trial, Molyneux et al.
Zilver PTX was recently evaluated in a large multicenter, multinational randomized, controlled trial and a complementary multinational, multicenter, single-arm clinical study [ 13– 15].
rFVIIa has indeed been tested in a multicenter multinational randomized controlled trial [ 7] and was shown to decrease hematoma enlargement, disability, and 90-day mortality.
