Although the contribution of the individual steps of what is called best practice is uncertain, multimodal intervention strategies were effective even if the combination of the specific interventions varied across the studies [ 123].
The importance of utilizing a multimodal treatment strategy that incorporates both medication and non-drug interventions is recognized by all ADHD clinical guidelines [ 1, 17, 66, 75, 91].
Furthermore, concurrent non-drug treatments, including behavioural therapy, should all be considered as part of a multimodal treatment strategy.
Multimodal treatment strategies have been established and are presently regarded as standard for many tumor stages.
New multimodal treatment strategies require the information of tumor stage, as it defines enrollment into neoadjuvant therapy approach.
Recently, new concepts of multimodal treatment strategies for locally advanced gastric carcinoma have been investigated [ 7, 8].
There is growing evidence to support multimodal treatment strategies which combine exercise, manual therapy and psychological approaches.
The increase of AHC and observed compliance show, that the multimodal intervention program based on the WHO strategy led to improved HH compliance.
Nevertheless, the effects we show here may provide some worthwhile benefit if the olfactory mucosal cell transplant were to be part of a multimodal intervention, as is more likely to be developed as a future therapeutic strategy (Thuret et al., 2006).
A similar multimodal approach has been incorporated in this study, and an extended follow-up of the intervention strategy was conducted [ 11].
