Sentence examples for multimodal compound from inspiring English sources

Vortioxetine is a novel multimodal compound that has recently been approved by the FDA for the treatment of major depressive disorder (MDD).

Vortioxetine is a novel multimodal compound that has recently been approved by the Food and Drug Administration FDAA) of the United States of America for the treatment of MDD.

Herein, we further explore LA as a privileged structure for developing multimodal compounds to investigate AD.

We review the available information for the two multimodal compounds vortioxetine and vilazodone, which are examples of this approach.

Clinical results with these multimodal compounds will provide valuable insights into whether exploiting serotonergic modulation of glutamate transmission is an effective strategy in treating depression.

There are currently two multimodal compounds with clinically documented antidepressant activity: vilazodone, which is approved for clinical use in the U.S., and vortioxetine, which is undergoing regulatory review.

The multimodal compounds vortioxetine and vilazodone are examples of this approach with diverse mechanisms, and their different clinical effects will provide valuable insights into serotonergic modulation of glutamate transmission for the potential treatment of depression and associated cognitive dysfunction.

The multimodal compounds vilazodone and vortioxetine are examples of this approach with diverse mechanisms, to indirectly modulate glutamate transmission by respectively targeting the 5-HT1A receptor, or 5-HT3, 5-HT7A, 5-HT1B along-HT1B receptors along with the SERT.

Given the complexity of the serotonergic modulation of glutamate, it is not possible to predict the net effect that multimodal serotonergic compounds will have on glutamate neurotransmission.

Detection of MSCs might consider multimodal approaches including SPIO and PFC compounds.

Finally, targets with less than 30 annotated compounds exhibit multimodal pairwise similarity distributions and, consequently, model performance is low, with standard deviations in the 0.50-1.00 range of pIC50 unit (Figure 8).