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For a multilocus haplotype model, these values correspond to the population frequencies of haplotypes at time t.

Together with the infinitely-many-sites model for mutations, the simplified multilocus haplotype model is used to approximate the evolutionary dynamics of the data.

The likelihood is based on the proposed simplified multilocus haplotype model, which describes the ancestral process of haplotype extent under the joint effects of selection, recombination and mutation.

Given the position of the selected mutant, we propose a simplified multilocus haplotype model that can efficiently model the dynamics of the ancestral haplotypes under the joint influence of selection and recombination.

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The proposed method is novel in jointly modeling the multilocus haplotype pattern caused by recombination and mutation, allowing the analysis of haplotype data in recombining regions.

However, multilocus haplotype analysis based on simulations yielded a P = 0.00005 in the case control study and a P = 0.03 for the family-based association studies.

The input dataset contained, for each individual, the multilocus haplotype displayed.

For all subsequent analyses, we used a data set in which each multilocus haplotype was represented only once in each sample [55].

A multilocus haplotype network was generated using phylogenetic algorithms with migration [ 51].

We found no genetic variation among group A isolates, and this same multilocus haplotype (no.

To determine phylogeographical relationships among isolates, a multilocus haplotype network was constructed combining tub2 and EF1α.

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