Sentence examples for multilocus association analysis from inspiring English sources
Finally we apply the proposed LRT to multilocus association analysis for the binary genetic data.
Moreover, when a parametric multilocus association analysis was performed, significant values of associations were only observed in the Ibiza and Cosenza populations.
We implemented multilocus association analysis for four genes ELAVL4, PRKCB1, PTK2B and SOS2 across all the 200 replicates of the GAW17 data.
Finally we apply the permutation-based LRT to multilocus association analysis in the case control study, where the problem can be investigated under the framework of logistic mixed effects model.
Third, we further examined the effects of multiple SNPs on YOH by two types of genome-wide multilocus association analyses: p-value combination analysis and haplotype analysis with sliding windows of 3, 5, 7 and 9 SNPs.
The various tests we used are implemented in the program UNPHASED (http://www.rfcgr.mrc.ac.uk/̃fdudbrid/software/unphased/) [63], a suite of programs for association analysis of multilocus haplotypes from unphased genotype data.
To increase the test power, in addition to the single-locus association test, we used various multilocus association methods, including the p-value combination approach [29], haplotype analysis [27], [34] and interaction analysis [23] [26], [30], to compensate for the limitations of the single-locus association test and to examine fully the genetic complexity of hypertension.
Fourth, we performed genome-wide multilocus association tests using either the haplotype association test or p-value combination test.
Next, we verified the significant findings obtained from genome-wide multilocus association tests and the interaction tests.
Single-locus association tests, multilocus association tests and pair-wise gene-gene interaction tests were performed to identify young-onset hypertension susceptibility genes.
The fully conditional posterior densities for the multilocus association model (1) parameters are as follows.
