Sentence examples for multilineage commitment from inspiring English sources
These findings are also consistent with the observation that geminin restricts multilineage commitment in the early Xenopus embryo [ 33].
Hu, M. et al. Multilineage gene expression precedes commitment in the hemopoietic system.
A co-expression of multilineage markers preceding a commitment in the hematopoietic system was reported by Hu et al. [ 24].
Previous works have demonstrated that human MSCs express genes characteristic of multilineage cell type prior to unilineage commitment [54], [55].
Furthermore, ES cells exhibit transcriptional activity for many genes associated with lineage commitment and differentiation, similar to the phenomenon of multilineage priming (also known as multilineage preview) described in hematopoietic stem cells (Hu et al., 1997; Ye et al., 2003).
More importantly, these cells when exposed to appropriate differentiation culture medium in vitro, showed a multilineage differentiation potential and ability to overcome the mesodermal commitment by differentiating into hepatocytes.
During development, these immature thymocytes gradually lose their proliferative and multilineage potential, and initiate a T-cell developmental program, a process termed T-cell commitment.
It has been shown that mice ASC expressing ACTA2 present multilineage differentiation ability compared to ASC that do not express ACTA2 which only display adipogenic commitment [ 22].
Interestingly, this decreased stemness leads to multilineage differentiation in ECSLCs.
