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The hierarchical map equation can reveal rich multilevel organization in real-world networks.
With a novel search algorithm, we extract and illustrate the rich multilevel organization of several large social and biological networks.
Using the fundamental mathematics of information theory to exploit the duality between compression and pattern detection, we have shown how to reveal the multilevel organization of networks.
We hypothesized that such a multilevel organization of the network connectivity structure could be utilized to provide both visually attractive and biologically relevant network layouts.
The generic algorithm combines the traditional force-directed node placement method of Fruchterman and Reingold [ 23] with multilevel organization by recursively coarsening graphs in two phases.
For instance, when applied to the literature-curated Human Protein Reference Database (HPRD) network [ 60], the multilevel organization was able to visualize both the global and local network structures, such as the large number of peripheral protein nodes and highly interconnected sub-network modules, which were largely missed by the other layout algorithms in Cytoscape.
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In multilevel organizations, messages get distorted as they travel up and down the ladder of command.
Here, we demonstrate multilevel organizations of genetic landscape, candidate genes, and molecular networks associated with 328 stress and sleep traits in a chronically stressed population of 338 (C57BL/6J × A/J) F2 mice.
It explored in detail the context of multilevel organizations within the Gaza Strip.
In general, we find shallow hierarchical structures in globally interconnected systems and rich multilevel organizations in systems with highly separated regions.
In general, we find shallow hierarchical structures in globally interconnected systems, such as neural networks, and rich multilevel organizations in systems with highly separated regions, such as road networks.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com