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Our model study identified the COP9 signalosome as the key and multilayer regulator of dendritic arborization.
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Consistently, multilayer regulations of iPS factors have been identified to cooperatively regulate the pluripotency.
Furthermore, conditional mutations in the Apc gene, which is a negative regulator of the Wg pathway in flies, lead to ISC mitosis and epithelial multilayering, similarly to mammalian APC mutations, which promote gastrointestinal cancer (Cordero et al., 2009; Lee et al., 2009) (Fig. 3B,D).
NANOG is a key regulator of pluripotency.
Be your own regulator of financial products.
Regulator of banks.
VEGF is an upstream regulator of PI3K.
Cytokines are potent regulators of inflammation.
Caspases are important regulators of apoptosis.
Kinases are pivotal regulators of cellular physiology.
Some modifiers are regulators of gene expression.
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