Sentence examples for multifunctional regulator of from inspiring English sources
Ppargc1a is a multifunctional regulator of metabolism and mitochondrial biogenesis, and has been linked to regulation of glucose homeostasis, CR and a possible role in aging through a physical interaction with Sirt1 in liver [40].
Our findings indicate that mitofilin is a central component of MINOS and functions as a multifunctional regulator of mitochondrial architecture and protein biogenesis.
One of the principal roles of the multifunctional regulator of G-protein signaling (RGS) proteins is to terminate G-protein-coupled receptor (GPCR) signaling by binding to the G-protein Gα subunit, thus acting as GTPase-activating proteins (GAPs).
Like Dlx5, Runx2 (encoding two isoforms that differ at their amino-termini) is a multifunctional regulator of both chondrocyte and osteoblast differentiation [41] and the two factors have some remarkable parallels in both expression and function.
Collectively, the data identify p66Shc as a multifunctional regulator of B-cell trafficking.
Finally, HuR is a multifunctional regulator of RNA stability and recognizes a set of AU-rich sequences using its two N-terminal RRM domains [ 43].
Moreover, miRNAs are attractive candidates as multifunctional regulators of disease progression, because one miRNA can regulate an entire set of genes [ 20].
Two important multifunctional regulators of hematopoiesis, MIP1α [ 22] and Skil [ 23], were regulated in both peripheral and marrow-derived T-cells at initial diagnosis.
BMPs were first identified as inducers of ectopic bone formation in vivo [ 7] but were later found to be crucial multifunctional regulators of development [ 8].
The Arabidopsis receptor kinase FERONIA (FER) is a multifunctional regulator for plant growth and reproduction.
H. pylori's Fur protein is a multifunctional regulator that controls transcription of dozens of genes, some negatively and some positively, and variously in response to iron availability, pH and oxidative stress (Fig. 1).
