Bottini, N. & Peterson, E.J. Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.
Schilde, C., Araki, T., Williams, H., Harwood, A. & Williams, J. G. GSK3 is a multifunctional regulator of Dictyostelium development.
Collectively, the data identify p66Shc as a multifunctional regulator of B-cell trafficking.
Finally, HuR is a multifunctional regulator of RNA stability and recognizes a set of AU-rich sequences using its two N-terminal RRM domains [ 43].
This pointed once again to the multifunctional regulator of cell signal transduction and adaptor protein, 14-3-3ζ, 14-3-3γ 14-3-3γ 14-3-3γh less than half the number of interactions.
Many of these genes are involved in hepatocyte functions, suggesting that Prox1 is a multifunctional regulator of liver morphogenesis and of hepatocyte function [ 32].
p62/SQSTM1 serves as multifunctional regulator of cell signaling involved in selective autophagy, intracellular trafficking and the NRF2 antioxidant response (Ichimura et al., 2013; Calderilla-Barbosa et al., 2014).
Moreover, miRNAs are attractive candidates as multifunctional regulators of disease progression, because one miRNA can regulate an entire set of genes [ 20].
Two important multifunctional regulators of hematopoiesis, MIP1α [ 22] and Skil [ 23], were regulated in both peripheral and marrow-derived T-cells at initial diagnosis.
Spire and Cordon-bleu: multifunctional regulators of actin dynamics.
