Sentence examples for multifunctional receptor that from inspiring English sources

SCARB1 is a multifunctional receptor that mediates bidirectional lipid transport in the macrophage.

CD57, a marker used to identify poorly functional "senescent" T cells [ 15 ] 2B4, a multifunctional receptor that may have either inhibitory or stimulatory effects on T cells [ 16 ].

The CD91 receptor (low-density lipoprotein receptor-related protein [LRP1] or alpha 2-macroglobulin receptor [A2MR]) is a multifunctional receptor that recognizes hsp-chaperoned peptides, which are processed and presented by the MHC class I and MHC class II molecules.

ChemR23 is a multifunctional receptor that transduces the anti-inflammatory and proresolving effects of C-terminal chemerin peptides, including C15 and the lipid RvE1, as well as the proinflammatory effects of full-length chemerin [ 17 19].

The LRP1 is a multifunctional receptor that is expressed in a wide range of tissues, as well as in multiple malignancies, including colon cancer, renal cancer, and melanocytic tumours (de Vries et al, 1996; Desrosiers et al, 2006; Obermeyer et al, 2007).

A preponderance of evidence supports developmental and pathophysiological roles for the MET receptor tyrosine kinase, a multifunctional receptor that mediates distinct biological responses depending upon cell context.

The tetrameric arrangement and the negative charge distribution close to the active sites of the enzyme, have suggested the design of complementary multifunctional receptors that might bind to the active region of the protein blocking the approach of the substrate.

Interestingly, surface nucleolin expression and ligand internalization via surface nucleolin has often been associated with the expression of the low-density lipoprotein receptor-related protein-1, a multifunctional scavenger receptor that mediates the uptake of various ligands from the pericellular environment [7], [12], [20], [63].

As a member of the LDL receptor family, LRP1 is a large, multifunctional, endocytic receptor that is highly expressed in neurons (reviewed by Andersen [ 1]), activated astrocytes [ 2- 4], and microglia [ 5].

Multifunctional character of GAPDH was reported in macrophages where GAPDH serves as a surface receptor that is upregulated upon iron depletion (Rawat et al. 2012).

Megalin and cubilin are two multifunctional endocytic receptors that act in concert in certain tissues to mediate the uptake of a variety of lipoproteins and vitamin-carrier complexes [ 19- 21].