Sentence examples for multifunctional proteins such from inspiring English sources

This technique provides the opportunity to study these effects under controllable conditions, and is especially useful for multifunctional proteins such as dystrophin.

We propose that SUMOylation can act as a molecular switch in the active zone, controlling the interactions and defining the function of different pools of multifunctional proteins, such as RIM1α.

Since each assay measures a different aspect of cell death, a multifunctional protein such as TG2 might differentially modulate these different aspects and give contradictory results in different assays.

Hence, classical neofunctionalization has fallen out of favor in preference for models that begin with the duplication of a multifunctional protein, such as 'specialization' and 'subfunctionalization' models.

A large multifunctional protein such as APC is an excellent candidate for the existence of functional variants with different roles in various tissues, stages of development and physiological states.

It is with this background, interest in novel features of multifunctional regulatory proteins such as Fur and survival strategies of niche-specialists such as H. pylori, and with the long-range goal of better understanding H. pylori Fur's structure, function and regulatory circuitry, that we carried out the mutational analysis of H. pylori fur described below.

The present mutational analysis was begun after finding a mutation affecting H. pylori Fur's distinctive N terminal arm after multiple steps of selection for ever higher levels of Mtz resistance, and was motivated by interest in multifunctional regulatory proteins such as Fur and the medical significance of H. pylori and its resistance mechanisms.

Several multifunctional effector proteins (such as EspF and Map) common to C. rodentium and other attaching/effacing pathogens, cause host epithelial cell apoptosis as well as the disruption of intercellular tight junctions [ 37, 46, 47].

The amino acid residues in the Cx43- carboxyl terminus are targets of multifunctional protein kinases such as Ca2+/CaM protein kinase II (CaMKII), an enzyme known to play critical roles in Ca2+ homeostasis, transcription, apoptosis, and ischemic heart disease.

The multifunctional role of proteins such as those discussed here shows this to be a reasonable assertion.

Recently, a number of structurally diverse, multifunctional, ubiquitous host proteins – such as HMGB1 and heat shock protein 72 (have2) – have been categorised as 'alarmins' based on the following shared properties (Ref. 50) (Fig. 2).