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(iii) Nucleolin is an abundant multifunctional phosphoprotein of proliferating and cancerous cells [ 38- 41] and highly expressed in "b".
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In contrast, we did not observe any relationship between plasma OPN level and renal impairment or anemia, which suggests that this multifunctional phosphoprotein is not relevantly involved in these aspects of MM.
It is a multifunctional phosphoprotein that has been implicated in cell proliferation [ 10] as well as regulation of transcription, where it appears to be able to both repress [ 11] or stimulate [ 12- 13] transcription.
Nucleolin is a ubiquitous, nonhistone, nucleolar, multifunctional phosphoprotein that is also overexpressed in cancer cells.
Nucleolin is a ubiquitous, nonhistone, nucleolar, multifunctional phosphoprotein that is also overexpressed in cancer cells [16], [36].
It is a multifunctional phosphoprotein shuttling continuously between nucleolus and cytoplasm.
The nucleophosmin 1 (NPM1, localized on 5q35) gene encodes for a multifunctional phosphoprotein located primarily in the nucleolus.
Dishevelled (Dsh or Dvl) is a multifunctional phosphoprotein originally discovered in Drosophila and named for its disruptions in hair and bristle polarity (Fahmy and Fahmy 1959; Klingensmith et al. 1994).
For DcHEV strain 178C, similar to HEV4 and the 2 recently discovered wild boar HEV strains (11 ), ORF3 began at nt 5161 (Technical Appendix Figure) and ended at nt 5502, encoding a small phosphoprotein of 113 aa with a multifunctional C-terminal region.
Nucleolin is an abundantly expressed acidic phosphoprotein of exponentially growing cells.
Nucleolin is a ubiquitous expressed acidic phosphoprotein of exponentially growing cells.
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