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Importantly, many researches have focused on multifunctional nanoparticles for targeted delivery of bioactive and imaging agents as therapeutics and diagnostics.
Thus, the novel FePt@PPy NPs could be considered as promising multifunctional nanoparticles for further applications of photo-based diagnosis and treatment.
Owing to their good properties, the novel FePt@PPy NPs could be considered as promising multifunctional nanoparticles for further applications in PTT and PAI.
Nanotechnology has started a new era in engineering multifunctional nanoparticles for diagnosis and therapeutics by incorporating therapeutic drugs, targeting ligands, stimuli-responsive release and imaging molecules.
Highlighted examples illustrate the great versatility and interesting possibilities offered by these smart multifunctional nanoparticles for (bio sensing of relevant analytes operating both in static and dynamic modes.
(b) The QDs have big surface-to-volume ratio to accumulate several different functional groups that can use to diagnose multiple targets, therefore this condition obligates to design of multifunctional nanoparticles for high-quality imaging.
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In this work, we develop multifunctional nanoparticles (NPs) for co-delivery of the conventional anticancer drug docetaxel (DTX) and the second generation photosensitizer zinc-phthalocyanine (ZnPc) as potential dual carrier system for the combination of chemotherapy and photodynamic therapy (PDT).
These multifunctional nanoparticles were characterized for particle size, morphology and drug encapsulation.
Multifunctional nanoparticles are attractive for cancer therapies due to their potential to be designed to overcome both the extracellular and intracellular delivery hurdles present systemically and in tumors.
The UV vis spectra results showed that the multifunctional nanoparticles exhibited fluorescence enhancements for Cd2+ and Zn2+, and fluorescence quenching for Cu2+.
In addition, NP-CIK cells also enter into the liver, spleen, kidney, etc.; however, compared with available reports, the amount of gold nanorods loaded with human CIK cells in the tumor site is higher than the amount of antibody-conjugated gold nanorods, which show that human CIK cells should be a good delivery system for multifunctional nanoparticles, therapeutic gene, or drugs.
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