Sentence examples for multifunctional enzyme complex from inspiring English sources

In some anaerobic thermophilic/thermotolerant microorganisms, few cellulases are organized as unique multifunctional enzyme complex, called the cellulosome.

Mammalian FAS is a multifunctional enzyme complex that catalyses the synthesis of palmitate from acetyl-CoA and malonyl-CoA with NADPH as a provider of reducing equivalents (Kuhajda, 2006).

In this regard, we report the first example of a set of fluorescent real-time sensors capable of simultaneously monitoring all three of the catalytic activities of the proteasome and thereby furnish the catalytic signature of this multimeric multifunctional enzyme complex.

Nonribosomal peptides are biosynthesised by nonribosomal peptide synthetases (NRPS), multifunctional enzyme complexes which assemble either proteinogenic or nonproteinogenic amino acids into the final peptide structure in an assembly line fashion [ 27].

Interestingly, in contrast to the metabolism of mycobacteria, the host FASII differs from FASI in that the latter uses a single multifunctional enzyme-ACP complex to initiate fatty acid biosynthesis [ 65].

But ACACB is also a complex multifunctional enzyme system, which controls fatty acid oxidation through the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I.

In this review, we discuss several of nature's most notable multifunctional enzyme systems including the AROM complex and tryptophan synthase, each of which provides new fundamental insights into the structural organization of metabolic machinery within living cells.

These strategies may be conducted separately or in combination, and they involve the following dominant microbial paradigms: cell-free enzyme systems, multi-enzyme (cellulosome) complexes, and multifunctional enzyme systems.

Channeling of this kind can theoretically occur within multifunctional enzymes, tightly associated multienzyme complexes, or transient enzyme complexes (1, 2).

Free enzymes, multifunctional enzymes and multi-enzyme complexes (cellulosomes) are common configurations of microbial cellulase systems.

Of these, FabH acts as a pivotal link between a mammalian-like Fatty Acid Synthase I (FAS-I), a multifunctional enzyme that conducts de novo synthesis of C16 and C26 fatty acids, and Fatty Acid Synthase-II (FAS-II) a bacterial-type multi-enzyme complex that extends FAS-I products to long chain C48 56 fatty acids termed meromycolic acids.