Sentence examples for multifunctional domain from inspiring English sources

The PHD is a multifunctional domain that is involved in protein interactions and is an E3 ligase.

Whilst CTNNBL1 lacks significant sequence similarity to other proteins, secondary structural predictions suggest that CTNNBL1's central region might comprise an armadillo domain, a multifunctional domain that is found in several unrelated proteins [1,6].

MA121.1 (p = 9.30809e-02) is a binding site of ARR10, whose multifunctional domain is responsible for both nuclear localization and DNA binding [ 50]; MA0096.1 (p = 9.96644e-02) is a binding site of two flower-specific bZIP proteins [ 51].

Due to its multifunctional domains, FKBP51 regulates several biological processes in the cell, through protein-protein interaction [1].

Nucleoli are now recognized as multifunctional domains containing some 700 different types of proteins involved in several fundamental processes of cell life such as ribosome biogenesis, RNA maturation, cell cycle and apoptosis regulation [1] [3].

The present survey investigated the assembled S. minutum genome and identified 25 candidate polyketide synthase (PKS) genes that encode proteins with mono- and multifunctional domains.

Moreover, the possibility to modify the natural properties of S-layer proteins by genetic manipulations and to incorporate single or multifunctional domains of other proteins while maintaining the self-assembly capability has led to a broad spectrum of applications in numerous areas of both, life and material sciences.

Finally, the carboxy-terminal multifunctional E/F domain holds the ligand-binding domain as well as sites for cofactors, transcriptional activation (AF-2) and nuclear localization [ 63].

The interactions between the various domains of the DGC YdaM, the transcription factor MlrA and the multifunctional GGDEF+EAL domain protein YciR seem to fall into three classes, that is, strong, weak and conditional interactions.

The problem occurs if such a multifunctional binding domain is part of two or more output subgraphs as shown in Figure 3C.

The nucleolus plays several crucial functions in the nucleus: in addition to its function as ribosome factory of the cells it is a multifunctional nuclear domain, and nucleolar activity is linked with several pathologies.