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Survivin embodies this multifunctional diversity, and compelling data accumulated over a decade have elucidated many of its essential roles as a regulator of mitosis [ 17], a broad cytoprotective factor [ 18, 19], and an effector of cellular adaptation to stress [ 20, 21].
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The multifunctional diversities existing in nature provide clues to speculate the structure property function relationships.
Its multifunctional nature, structural complexity, diversity of isoforms, and splice variants all characterize this protein kinase and make study of its activity and function challenging.
We explore drivers, consequences and entry points for tree diversity management to achieve multifunctional agriculture.
Plants might thus have evolved aspects of gene regulation diversity by incorporating a multifunctional PRC1-like subunit, thus compensating for having a unique LHP1 gene compared to 3 to 5 in animals.
HDL proteome diversity was compatible with multifunctional roles of HDL on lipid metabolism, oxidation, immune reaction, inflammation, and hemostasis.
Diversity is, instead, diverse.
Therefore, efforts to build dynamic covalent systems with more than one reversible reaction have been explored.[ 26, 28– 32] Although reversible cascade reactions provide easy access to multifunctional structures, parallel reactions generate structures of higher diversity.
In this context the preservation of floristic diversity is stressed to be one important goal of modern, multifunctional agricultural land use.
T-cell intracellular antigens (TIA) are multifunctional proteins that operate as ancient DNA/RNA trans-acting regulators to broaden transcriptome and proteome diversity.
The lipopeptides like surfactin or iturin are synthesized by multifunctional enzymes encoded by large gene clusters (Kleinkauf and von Döhren 1995; Marahiel et al. 1997) and exhibit large diversity.
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