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All the latter individual efficiencies were included in a multifunctional development factor (MDF) resulted in 0.626 for P1, 0.326 for P2, and 0.679 for P3, where the higher value corresponded to the highest efficiency.
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BMP-6, an important growth factor involved in the regulation of bone development, has been found to be a multifunctional growth factor.
BMP2 is a multifunctional growth factor and a homodimer of two 114 peptides subunits, and two receptor-binding motifs have been identified in the BMP2 ligand.
Hepatocyte growth factor (HGF) is a multifunctional growth factor produced by stromal cells.
TGF- β is a multifunctional growth factor that regulates cell fate, including EMT and apoptosis.
EGF is a multifunctional growth factor, which causes activation of many cytoskeletal proteins including cofilin.
It is a multifunctional growth factor that regulates proliferation, differentiation of cells, protein synthesis and angiogenesis.
Transforming growth factor β1 (TGF-β1) is a pleiotropic, multifunctional growth factor with fibrogenic and immunomodulatory properties.
TGFB1 is the prototype member of the TGFB-superfamily comprising multifunctional growth factors with numerous cell and tissue functions such as cell cycle control, regulation of early development, differentiation, extracellular matrix (ECM) formation and chemotaxis.
AMF/GPI is a multifunctional cytokine that exhibits multifunctional growth factor-like activity via a unique cognate 78 kDa (glycoprotein 78, gp78) seven-transmembrane glycoprotein receptor (autocrine motility factor receptor, AMFR) [ 10].
Bone morphogenetic proteins (BMPs) are multifunctional secreted growth factors regulating a broad spectrum of functions in numerous systems.
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