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Glycosaminoglycans (GAG) are multifunctional components of the extracellular matrix (ECM) involved in different steps of the regulation of cellular differentiation.
Sulfated glycosaminoglycans (GAG) are multifunctional components of the extracellular matrix and are involved in the regulation of adhesion, proliferation and differentiation of cells.
As multifunctional components of vascular structures, endothelial (progenitor) cells have been utilized in cellular therapies and are required as an important cellular component of engineered tissue constructs and in vitro disease models.
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A portion of the PTEN molecule, including the phosphatase-like domain, exhibits significant similarity to the N-terminal domain of tensin, a multifunctional component of integrin-mediated focal adhesions known to participate in cell motility and cell adhesion [ 50, 54].
One example of this comes from the preclinical experience gained with adipokine osteopontin (OPN), also called "early T cell-activation gene 1," a multifunctional component of the extracellular matrix that has been linked to a plethora of autoimmune diseases [ 164].
Both enzymes behaved similarly at 50°C and 60°C as shown in Figure 4. CHIKV nsP2 is an essential and multifunctional component of the viral replicase complex [ 10, 26, 27].
CagD appears to serve as a potential multifunctional component of the T4SS which may be involved in CagA injection at the inner membrane and may localize outside the bacteria to promote other responses in host cells [ 51].
Another option is the design of multifunctional components to reduce the number of end of life materials that need to be dealt with.
In particular, algal photobioreactors that use Chlorella vulgaris have been identified as potential multifunctional components for use as part of such a bioregenerative life support system (BLSS).
Recently, carbon nanomaterials with porous structure and multifunctional components have also been designed and constructed for biomedical applications.
We demonstrated that the simultaneous reinforcement and plasticization effect on the polymeric matrix by the novel multifunctional component should be ascribed to the soft organic coating and the unique flowability of such surface-functionalized CNTs.
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