Considering that tumor development is generally multifactorial, therapy with a combination of agents capable of potentiating cytotoxic effects is promising.
Multifactorial therapy (lipid normalization, tight control of hypertension, near-normal glucose control, anti-platelet therapy) is cost-effective in preventing complications in patients with diabetes and cardiovascular disease.
With a multifactorial etiology, therapy that focuses on one facet has limited therapeutic efficacy [ 6, 7].
The aetiology of the post-transplant weight loss is likely to be multifactorial, including increased energy expenditure related to both increased activity and postprandial thermogenesis secondary to endogenous insulin secretion, as well as a central effect of immunosuppressive therapy on appetite.
Lastly, the Steno-2 trial compared the effect of a multifactorial intensive therapy (n = 80) with that of conventional treatment (n = 80) on modifiable risk factors for cardiovascular disease in patients with Type 2 diabetes [ 55].
In this trial, doctors and co-medicals collaborate to treat the DN patients to prevent the deterioration of DN by multifactorial intensive therapy.
Hundreds of miRNA target genes are predicted by computer analysis, which means that miRNA therapy has more multifactorial effects on tissue regeneration compared with single growth factor administration.
Patients with SAF should receive intensive cardiac therapy based on a multifactorial approach including tight ambulatory monitoring, regular screening for progression of coronary artery disease, optimum medical therapy of heart failure, and finally prophylactic implantation of a cardioverter defibrillator.
This study evaluated the effectiveness of a multifactorial intervention on improving the therapeutic adherence in chronic obstructive pulmonary disease (COPD) patients with scheduled inhalation therapy.
Septic AKI is caused by multifactorial impacts on the kidney.
