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Upon chronic exposure to minimal doses of hydrogen peroxide, SH-SY5Y cells displayed a multifactorial response to the stressor.
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Therefore, all the conditions that lead to HIPK2 deregulation would end in a multifactorial response leading to tumor chemoresistance by strongly affecting p53 transcriptional activity and apoptosis on one hand and HIF-1 activity on the other hand.
The end result would be a multifactorial response leading to 5FU resistance.
S. cerevisiae grows far better at acidic than neutral or alkaline pH and consequently even a modest alkalinization of the medium represents a stress situation that is able to trigger a compensatory multifactorial response (for a review see [ 16]).
The multifactorial response of the brain and the complex signaling pathways involved therewith limits the therapeutic efficacy of several antioxidants in ameliorating hypobaric hypoxia induced memory impairment.
In addition, the L. interrogans transcriptome was evaluated in response to multifactorial conditions, upon exposure to serum [58].
Adoptive transfer experiments in mice delineated the need for a multifactorial vaccine-elicited immune response to protect against wildtype FV challenge.
Asthma is a complex multifactorial inflammatory disease characterized by airway hyper-responsiveness (AHR) in response to a wide variety of inhaled environmental antigens.
This multifactorial regulation limits the MMP response to menstruation, ensuring tissue damage is not prolonged.
(B HV2) Thus, both women and health professionals viewed the cause of postnatal depression as multifactorial and often a social response to birth.
Therefore, we conclude that elevated cortisol concentrations in LP sows at the end of pregnancy can affect HPA activity in offspring, especially in response to a multifactorial stress such as weaning.
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