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The mechanisms of such a hyporeactive state are unclear and are probably multifactorial, related to sepsis [ 12], chemotherapy [ 13] or neutropenia per se.
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Tl uptake is considered to be multifactorial relating to the Na K ATPase system, tumour vascularity, cellular membrane permeability and tumour viability.
Hypoalbuminemia is multifactorial and related to poor nutrition, inflammation, and comorbid disease.
The causative factors for the various signs and symptoms of TMD are multifactorial and related to psychological, functional and structural features [4].
Drug resistance represents a complex and multifactorial phenomenon related to tumor microenvironment, e.g. hypoxia, acidosis and inflammation as well as the neoplastic cell itself [3].
The pivotal role of mitochondria in energy production and free radical generation suggests that the mitochondrial genome could have an important influence on the expression of multifactorial age related diseases.
Takotsubo cardiomyopathy (TCM) is a multifactorial, stress related cardiomyopathy, rarely reported in association with thyrotoxicosis.
Furthermore, MDD is thought to be a multifactorial disease related to both environmental and genetic factors.
In fact, microaspiration is a multifactorial process related to mechanical ventilation, tracheal tube, enteral nutrition, and general factors.
It is well established that macular degeneration is a multifactorial disease related to age, genetics and a host of environmental factors such as light exposure and smoking.
The major psychiatric disorders such as schizophrenia (SZ) and major depressive disorder (MDD) are thought to be multifactorial diseases related to both genetic and environmental factors.
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