Sentence examples for multifactorial pathology from inspiring English sources

Alzheimer's disease (AD) is a multifactorial pathology that requires multifaceted agents able to address its peculiar nature.

Low back pain is acknowledged widely to be a multifactorial pathology with a variety of symptoms, dysfunctions, and a number of possible sources of pain.

Still, the complexity of this multifactorial pathology reduces the translatability to clinical practice of data derived from genetically-modified animals because therapeutic interventions targeting these specific genes do not take into account other contributing genes that participate in the pathogenesis of the disease (Miller et al. 2013).

Traumatic brain injury (TBI) is a multifactorial pathology with great interindividual variability in response to injury and outcome.

Symptomatic osteoarthritis (OA) is now widely accepted as being a multifactorial pathology affecting the whole joint complex [ 1].

HSP has a multifactorial pathology in which a wide variety of pathogens, drugs, and other environmental exposures have been involved [ 3].

In complex multifactorial pathologies, such as multiple sclerosis, numerous mechanisms may ameliorate disease.

Inflammatory bowel diseases (IBD) are described as multifactorial pathologies with an uncontrolled immune response leading to inflammation in genetically predisposed individuals.

Nonetheless, it is now apparent that CD4+ T cells individually are unable to drive this multifactorial autoimmune pathology.

Therefore, we hypothesized that loss of SigR1 function contributes to a vicious circle including ER stress, defective autophagy and altered calcium signaling that causes multifactorial ALS pathology.

Such strategies are increasingly relevant for the development of successful combination therapies for patients suffering from complex, multifactorial cardiometabolic pathologies.