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This result is consistent with recent genome-wide selection experiments in Eucalyptus showing that a multifactorial model of a few hundred small effects throughout the genome contribute additively to height growth25, in contrast to earlier suggestions of the existence of a relatively small number of loci of larger effect as reported in several biparental QTL mapping studies26.
Inspired by causal concepts in the disease literature, Meeuwisse (1994a) created his new multifactorial model of athletic injury aetiology.
We then incorporated these findings into a multifactorial model of microvascular pathophysiology based on current evidence.
In general, our data are well in line with the multifactorial model of fears and phobias (Muris and Merckelbach 2001).
Such findings support the multifactorial model of gastric pathology that includes the host, H. pylori, and the environment [ 13, 36, 39].
Results support a multifactorial model of perceived barriers to mental health service use that includes practical barriers, lack of knowledge, and negative anticipatory emotions related to service use.
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Multifactorial models of risk have been proposed for explaining transmission of risk from parent to offspring of parents with non-affective psychosis [ 5] bipolar disorder [ 8], depression [ 9], and with broader diagnoses of SMI [ 10].
We also provide age-stratified LRs for ER alone and grade alone, which, although not as predictive as ER and grade combined, will facilitate inclusion of minimal pathology information in multifactorial modeling of individually rare variants.
Penn et al. [ 1] argued that multifactorial models of schizophrenia, including only non-social cognitive processes i.e. 'neurocognition', did not adequately explain the social functioning impairment in schizophrenia.
These findings are compatible with the multifactorial model and provide an example of the interaction of genetic and environmental factors.
Moore and Stuart (2005) take a bio-psycho-social perspective toward the relationship between drugs and violence that posits a multifactorial model whereby the risk of violence increases as a result of both distal (biological and developmental factors) and proximal (environmental) factors.
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