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Prostate cancer (CaP) is a disease with multifactorial etiology that includes both genetic and environmental components.
However, HIV-associated diarrhea remains common due to a multifactorial etiology that includes infection, malignancy, enteropathy, and antiretroviral treatment.
Nowadays, degenerative rotator cuff disease is considered to be of multifactorial etiology that includes both extrinsic and intrinsic mechanisms.
Serum lipids have a multifactorial etiology that is determined by a large number of environmental and genetic factors [ 1].
Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors.
Microbiological aspect of periodontitis and especially aggressive periodontitis is peace of the complex multifactorial etiology that should be taken in consideration to help in better mentoring and treatment of this entity.
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Preterm labor and stillbirth are common endpoints with multifactorial etiologies that perturb, usurp, or activate the normal processes of parturition.
With a multifactorial etiology, therapy that focuses on one facet has limited therapeutic efficacy [ 6, 7].
We believe that EMND, just as ALS, may have a multifactorial etiology and that oxidative stress is a major contributing/predisposing factor, i.e., sufficient cause, in motor neuron death but not necessarily the sole etiologic agent/factor.
This, of course, is just what would be predicted by a model of complex multifactorial etiology, but it emphasizes that we are not finding genetic variants that are necessary and sufficient for causing dyslexia.
The concept of multifactorial etiology of BEN anticipates that a combination of polymorphic gene variants and various environmental factors causes an increased risk for the disease.
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