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Despite the multifactorial effects of CSD on brain pathophysiology, it is important to remember that many people with migraine do not experience visual aura and some with visual aura do not report headache.
We investigated the multifactorial effects of long-term minimal peroxide exposure upon SH-SY5Y neural cells to understand how they respond to the continued presence of oxidative stressors.
Apart from being a radical scavenger, the multifactorial effects of GA encompass also the inhibition of cyclooxygenases (COXs) and of lipoxygenases (LOXs).
The multifactorial effects of telmisartan shown in this study could, therefore, provide synergistic benefits in patients with hypertension and other cardiovascular risk factors, such as glucose intolerance.
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Reactive oxygen metabolites have multifactorial effects on the regulation of cell growth and malignant invasion.
The next section of papers considers the multifactorial effects on the initiation and morphogenesis phases of dental development.
The multifactorial effect of Lodamin treatment on angiogenesis, inflammation, vascular hyperpermeability and edema was studied in the DTH reaction.
Due to the multifactorial effect of TG2 on cell death pathways, specific conclusions about the role of this protein in cellular death remain elusive.
This study highlights the possibility of multifactorial effect of known risk factors for the pathogenesis of mixed cholesterol GS and black pigment GS.
Instead, it is likely a multifactorial effect of HER2 overexpression increasing the risk of CNS metastases [ 9– 11], the prolonged survival of trastuzumab-treated patients allowing CNS metastases to become symptomatic [ 17– 19], and the inability of trastuzumab to effectively cross the blood brain barrier [ 22].
In the second paper a particular aspect of the multifactorial effects, the role of human sex chromosomes in dental development is reviewed while from the multilevel effects the third paper focuses on epithelial histogenesis during tooth development.
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