Sentence examples for multifactorial diseases are from inspiring English sources

Many research articles disclosing the development of such compounds for treatment of multifactorial diseases are published during last 7 years.

This is important since polygenic multifactorial diseases are likely caused by many alleles that confer a small individual effect but a high risk in combination.

Multifactorial diseases are, however, characterised by complex gene-environment interactions [ 1].

It is possible that the effects of epistasis in multifactorial diseases are relatively modest.

In particular, while the Mendelian diseases are due to causative rare mutations in specific genes (causative gene) and are inherited according to Mendel's laws, multifactorial diseases are caused by an interplay between several genetic and environmental triggering factors [ 2, 4].

Highly penetrant genetic disorders are caused by a single mutation or a few genetic variants at most, whereas complex or multifactorial diseases are influenced by many genetic variants as well as environmental factors.

Personal genome testing for multifactorial diseases is conducted on the basis of genetic profiling.

Current personal genome testing for multifactorial diseases is not likely to pass the test in either perspective.

A third main ELSI associated with personal genome testing for multifactorial diseases is the legal and societal issue of regulation.

Identification of the culprit genes underlying multifactorial diseases is one of the most important current challenges of molecular genetics.

Our understanding of the genetic basis of multifactorial diseases is improving, but the currently identified susceptibility variants contribute only marginally to the development of disease.