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The GLM accounts for the multifactor design of this study.
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Multilevel multifactor design was used for construction of the calibration and validation sets [33].
Multilevel multifactor design was used for construction of calibration and validation sets.
To compensate for such effects, we accounted explicitly for the paired nature of replicates using a multifactor design [ 54].
The prediction power of the different models was compared using a validation set of 8 mixtures prepared as per the multilevel multifactor design and results were statistically compared using two-way ANOVA test.
The significance of differential gene expression was determined using DESeq package for multifactor design [ 13] in R software (R 2.14.0; DESeq release 1.6.1) (Additional file 1: Figure S6C).
A statistical multifactor design was employed to obtain more precise results.
The obtained data statistically analyzed in ANOVA table using multifactor design.
The methods used in analytical studies encourage the exploration of mechanisms through multifactor designs, contextual variables introduced through blocking and replication over time.
In the area of multifactor experimental design for exploring response surface, hybrid designs, considered as alternatives to central composite designs, refer to a class of saturated or near-saturated second-order designs that allow experimenters to fit a quadratic model with a minimal or near-minimal number of runs.
In conclusion: in all over the design of the device a multifactor approach would be adopted: a right combination of alloy composition, "surface shape", lubricant oil and alloy grains dimension, should be considered to avoid failures.
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