Its multifaceted roles in a spectrum of pivotal biological functions, such as metabolic regulation, tumor suppression, apoptosis and other stress response signaling pathways, and also aging processes, have brought this sirtuin to limelight (Giblin et al., 2014).
This variety of perceptual communication dysfunctions may underlie the multifaceted characteristics of the autistic spectrum disorder.
Parasites of the genus Leishmania cause leishmaniasis, a multifaceted disease presenting a wide spectrum of clinical manifestations.
No clear definition of endothelial dysfunction has been established so far, and this multifaceted disorder actually encompasses a spectrum of disturbances in vasomotor responses, antithrombogenic properties, vascular permeability, leukocyte recruitment and endothelial cell proliferation.
This vast interpretive spectrum converges in her multifaceted role in the play "Phaedra(s)," at BAM's Harvey Theatre, Sept. 13-18.
The scope of his entire career to date, which also includes documentaries, grand-scale historical frescoes, and satirical fantasies, indicates the colossal cinematic armamentarium that he would bring to bear on a widely contextualized and multifaceted view of African-American lives — a spectrum far greater than a commercially produced Hollywood movie would be able to contain.
This analysis was then considered, along with the previously collected TRIAD focus group data analyses, to create a conceptual model of the multifaceted impact of diabetes medication across the spectrum of delivery systems.
Instead of viewing these conditioning factors as providing a rich spectrum of different insights into a multifaceted reality, the judger dismisses such factors as so many distorting lenses that compromise the ability of these groups to see the world "objectively," at least as defined by the judger.
The document also recommends a single category for autism spectrum disorders, unifying what has been a multifaceted and complicated diagnostic scale.
It was clear that there is a spectrum, ranging from an organic link with communities and multifaceted community development activities established over years in political struggle (as in El Salvador), to more of a 'health service' relationship (as in Brazil).
As presented herein, Akt1, a multifaceted kinase which mediates various kinds of upstream signals to a diverse spectrum of substrates, plays multiple roles in bone cells as well as other cell types reported.
