Thus, Clu is a multifaceted protein whose cellular and developmental roles are just beginning to be elucidated.
It has multifaceted roles and is involved in several pathologies [ 38].
Osteoprotegerin (OPG) is a glycoprotein that has multifaceted role and is associated with several cancer malignancies like that of bladder carcinoma, gastric carcinoma, prostate cancer, multiple myeloma and breast cancer.
Within this multifaceted role, integrins have been shown to be molecular determinants of glioma invasion (5, 6, 18, 90, 110).
Instead, the extensive list of diverse cellular events involving Gαq-linked signals suggests that Gαq subfamily members have multifaceted roles in signal transduction which are not yet fully appreciated.
In the lung, these pathways play a multifaceted role; their activation is critical for lung development, while their deregulation can lead to inflammatory diseases such as pulmonary fibrosis and cancer transformation.
Given recent developments in our understanding of its molecular properties, VitD probably has a multifaceted role, which cannot be appreciated by examining hard clinical endpoints such as mortality.
In this domain, the team's role is multifaceted.
SIRT1 has been ascribed multifaceted roles in the regulation of proper metabolic homeostasis by maintaining lipogenesis, gluconeogenesis, fatty acid oxidation and others (Chang and Guarente, 2014).
BMSPCs have multifaceted roles in an adult organism most importantly being involved in lymphohematopoiesis [ 7] and immune surveillance [ 13].
