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The multifaceted functions of sirtuins in cancer.
These results unveil previously unrecognized multifaceted functions of β-catenin in the establishment and drug-resistant properties of MLL stem cells, highlighting it as a potential therapeutic target for an important subset of AMLs.
Such activities illustrate the flexibility and multifaceted functions of p53 variants.
In summary, we have uncovered multifaceted functions of a small molecule previously widely regarded as a replication inhibitor.
Together with other 22 Rho GTPases, RhoA contributes to multifaceted functions of blood cells in various physiologic processes and pathologic states.
Given the multifaceted functions of AA in plants, there is a need to advance our understanding of how plants regulate the biosynthesis and accumulation of AA.
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In his installations, at the HL Holocaust Center in Oslo and the Jewish Museum Berlin, among other places – the printed word take on the multifaceted function of the overtones of his doublebass, in varying states of motion and transparency, floating through the space through various means of projection, resonating now metaphorically, with the associations in our minds.
However, recent studies demonstrated a multifaceted function of p53 during specific differentiation programs.
Further, LF82Δhfq mutants were non-motile, impaired in cell invasion and highly sensitive to various chemical stress conditions, reinforcing the multifaceted function of Hfq in mediating bacterial adaptation.
Mechanical properties of the cornea play a central role to its multifaceted function of serving as both a physical barrier and the primary refractive element in the eye.
Another alternative possibility regarding the multifaceted function of H2A.Z, at least within the vertebrate lineage, could be related to the presence in these organisms of two different H2A.Z variants, H2A.Z-1, and H2A.Z-2, (Fig. 2) that have been described at the beginning of this section [ 10, 11].
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